THE FIRST SUCCINYLOME PROFILE OF TRICHOPHYTON RUBRUM REVEALS LYSINE SUCCINYLATION ON PROTEINS INVOLVED IN VARIOUS KEY CELLULAR PROCESSES

The first succinylome profile of Trichophyton rubrum reveals lysine succinylation on proteins involved in various key cellular processes

Abstract Background Dermatophytes, the most common cause of fungal infections, affect millions of individuals worldwide.They pose a major threat to public health because of the severity and longevity of infections caused by dermatophytes and their refractivity to therapy.Trichophyton rubrum (T.rubrum), the most common dermatophyte species, is a pro

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Lewy and his inclusion bodies: Discovery and rejection

ABSTRACT Fritz Jacob Heinrich Lewy described the pathology Bats of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy body diseases.In 1912, he published his seminal study, followed soon after by an u

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